Breast Surgeons Live
Back to Activities List
Session Title:
Revisiting a Changing Dogma: BCT vs Mastectomy for Early-Stage Disease
Date & Time:
January 13, 2026, 7:00 PM–8:00 PM ET
Length:
1 Hour
CME Deadline:
January 13, 2027
This activity is open to members only:
Log InTarget Audience:
Surgeons with a special interest in the treatment of breast disease.
Objectives:
coming soon
Description:
Long-term data from NSABP has demonstrated equivocal survival for patients with breast cancer regardless of if they undergo mastectomy or breast conserving therapy (BCT). However, recent contemporary data has begun to challenge this dogma with some data suggesting BCT may provide a survival benefit. Simultaneously, recent trials have demonstrated the safety of patient eligibility for BCT with multifocal disease and advances in nipple and skin-sparing mastectomies have demonstrated long-term safety and positive patient reported outcomes. This session will review the latest evidence in these topics to ensure surgeons are well equipped to provide contemporary evidence-based surgical recommendations for patients with breast cancer.
Agenda:
Welcome and Introduction
Kelly Hunt, MD, FACS, and Olga Kantor, MD, FACS
BCS and RT as Standard of Care for Most
Kari Rosenkranz, MD, FACS
Don't Push the Envelope — Mastectomy Reigns King
Barbara Smith, MD, PhD, FACS
Faculty:
Moderator—Kelly Hunt, MD, FACS
University of Texas MD Anderson Cancer Center
Houston, TX
Moderator—Olga Kantor, MD, FACS
Brigham and Women's Hospital
Boston, MA
Kari Rosenkranz, MD, FACS
Dartmouth-Hitchcock Medical Center
Lebanon, NH
Barbara Smith, MD, PhD, FACS
Massachusetts General Hospital
Boston, MA
References:
- Fisher B, Anderson S, Bryant J, Margolese RG, Deutsch M, Fisher ER, Jeong JH, Wolmark N. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med. 2002 Oct 17;347(16):1233-41. doi: 10.1056/NEJMoa022152. PMID: 12393820.
- Chu QD, Hsieh MC, Lyons JM, Wu XC. 10-Year Survival after Breast-Conserving Surgery Compared with Mastectomy in Louisiana Women with Early-Stage Breast Cancer: A Population-Based Study. J Am Coll Surg. 2021 Apr;232(4):607-621. doi: 10.1016/j.jamcollsurg.2020.11.011. Epub 2020 Dec 7. PMID: 33301909.
- Shrestha P, Hsieh MC, Ferguson T, Peters ES, Trapido E, Yu Q, Chu QD, Wu XC. Higher 10-Year Survival with Breast-Conserving Therapy over Mastectomy for Women with Early-Stage (I-II) Breast Cancer: Analysis of the CDC Patterns of Care Data Base. Breast Cancer (Auckl). 2024 Sep 23;18:11782234241273666. doi: 10.1177/11782234241273666. PMID: 39328281; PMCID: PMC11425729.
- Chen K, Liu J, Zhu L, Su F, Song E, Jacobs LK. Comparative effectiveness study of breast-conserving surgery and mastectomy in the general population: A NCDB analysis. Oncotarget. 2015 Nov 24;6(37):40127-40. doi: 10.18632/oncotarget.5394. PMID: 26517676; PMCID: PMC4741884.
- Agarwal S, Pappas L, Neumayer L, Kokeny K, Agarwal J. Effect of breast conservation therapy vs mastectomy on disease-specific survival for early-stage breast cancer. JAMA Surg. 2014 Mar;149(3):267-74. doi: 10.1001/jamasurg.2013.3049. PMID: 24429935.
- Hartmann-Johnsen OJ, Kåresen R, Schlichting E, Nygård JF. Better survival after breast-conserving therapy compared to mastectomy when axillary node status is positive in early-stage breast cancer: a registry-based follow-up study of 6387 Norwegian women participating in screening, primarily operated between 1998 and 2009. World J Surg Oncol. 2017 Jul 3;15(1):118. doi: 10.1186/s12957-017-1184-6. PMID: 28673296; PMCID: PMC5496325.
Disclosures:
coming soon
